Nodular Basal Cell Carcinoma Histology

They can also infiltrate into the adjoining soft tissues and nerves.

Nodular basal cell carcinoma histology. The metatypical bcc is an aggressive growth neoplasm arising in sun damaged skin and showing irregular tongues of tumor andor an admixed nodular bcc component a. Nodular basal cell carcinoma located on the cheek showing disruption of normal layering and hyporeflective oval structures white asterisks corresponding to tumor islands. Histopathology of skin basal cell carcinoma. Patients with bcc often develop multiple primary tumours over time.

Basal cell carcinoma bcc is a common locally invasive keratinocyte cancer also known as nonmelanoma cancer. Prostate cancer gleason grading. Bcc is also known as rodent ulcer and basalioma. Histopathology of lymph node nodular sclerosis in hodgkins disease.

Nodular basal cell carcinoma of skin is the most common type of bcc that is present as nodules on the skin usually in the head and neck area some nodules may grow to large sizes and ulcerate. Histology of basal cell carcinoma. The key feature of basal cell carcinoma at low power magnification is of a basaloid epithelial tumour arising from the epidermis figure 1. Programmed cell death physiology and pathology.

High power microscopy shows. The groups of basaloid cells have peripheral palisading of the nuclei and are surrounded by a myxoid stroma. An unreflective line is seen bordering the tumor islands white arrows corresponding to mucinous cleftingperipheral palisading often recognized in histology sections. The groups of basaloid cells are well demarcated from the stroma and show focal clefting from the stroma.

The basaloid epithelium typically forms a palisade with a cleft forming from the adjacent tumour stroma figure 2.